The Loneliest Place on Earth - OnOrbit has an interview with the crew doc of Concordia Station, a research outpost on the Antarctic Plateau (the world’s largest desert). It is is one of the coldest places on Earth: temperatures hardly rise above −25°C in summer and can fall below −80°C (the annual average is −54.5°C). There is no sunlight for 4 months out of the year, forcing the crew to live in perpetual darkness.
Due to its extreme and isolated location, ESA […] is involved by using the station as an analogue environment for its human spaceflight research program. There are arguments for and against why Concordia station and its overwintering crew may be considered a useful analogue environment, though some have argued against its reliability. Certainly the isolation you experience here is real. We are alone from February to November.
If you interested in reading more about what life is like in this kind of hostile environment, take a look at Chronicles from Concordia, a blog frequently updated by the crew at the station.